Chronic Migraine Rx with Botox®

Botox® (botulinum toxin A) has, following licensing by the Medicines and Healthcare products Regulatory Agency (MHRA) in 2010, been used as a procedure specifically designed to treat chronic migraine.

In the mid-1990s  patients who had received Botox® for other reasons began to notice an improvement in the intensity and number of headaches they got.

Medicals trials followed which found that people who suffered from chronic migraines, a sub-category of headaches, could benefit from using Botox® to help their pain and suffering. More trials were to follow to find out more information on the benefits of Botox® for chronic migraines.

Below you will find more details on this treatment which uses Botox® and the evidence behind it and its treatment of headaches and chronic migraines.

Botox® In Chronic Migraine Trials

Two PREEMPT trials recruited almost 1400 patients with chronic migraine and treated with either a Botox® procedure or a placebo. The people used for the trials suffered around 20 headaches per month with the majority of them either moderate or severe. The patients selected to receive Botox® were given injections of a fixed dosage at 12-week intervals throughout the duration of the trial.

The injections that triallists receive were placed in a total of seven precise parts of the head and neck. The total dosage ranged between 155-195 units. After two treatment cycles, the trial had found that those who had received Botox® to treat their chronic migraines had on average eight less days of headaches and migraines every month. After a year, almost three-quarters of those treated had less than half as many chronic migraines than they had before the trial began. Additionally, and in further testament to the benefit of the procedure, no serious or irreversible side effects were felt or reported during the trials.

How Does Botox® work to help Chronic Migraines?

It is thought that the use of botulinum toxin prevents chronic pain in migraines by reducing how certain nerve cell pain pathways worked in the trigeminovascular system. The trigeminovascular system is a key part of the pathway which belongs to the headache phase of a migraine attack. Further research, it is believed, will bring about the discovery of more detailed information regarding botulinum toxin and the nerves and cells that it acts upon.

Is Botox® the correct treatment for you?

Medical Dermatological Treatments which use Botox® is only for use on patients who suffer from migraines on in excess of 15 days per month.

If you have been diagnosed with Chronic Migraine and you feel your treatments are ineffective, please book a consultation to explore if Botox maybe your next option. Although we do not administer this treatment ourselves at the moment, we will refer you to an appropriate  specialist after the consultation.

Who Can Administer Botox® for Chronic Migraine?

The administering of Botox® treatments is restricted to a small number of specialist headache centres. However, as time progresses, we expect to see an increased amount of trained specialists who are able to administer the treatment for chronic migraines, including treatment delivered by our specialist injectors at at 23MD.

If you have been diagnosed with Chronic Migraine and your you feel your treatments are ineffective, please book a consultation to explore if Botox maybe your next option. Although we do not administer this treatment, we may refer you to an appropriate specialist.

Is Botox® For Chronic Migraines available on the NHS?

The treatment can be made available on the NHS for the patients who meet the correct criteria for people who suffer from chronic migraines. You can find out more about the process by contacting our experienced team who will be more than happy to provide you with the information you require.


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