There are few studies that have measured Vit D variation in people with depressive symptoms and how that changes through the seasons. In this study, Depressive symptoms and vitamin D were measured in 185 healthy women across 4 weeks.

Significant symptoms and vitamin D insufficiency were common, and differed by season. Initially low vitamin D levels were associated with clinically significant depressive symptoms across follow-up. Between-subjects differences in depression by season were partially explained by seasonal changes in vitamin D.

Findings are consistent with a the common association between low levels of vitamin D and clinically meaningful depressive symptoms.

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